C. Saayujya, K. Yousuf, Y. Hao, A. Hartley, K. H. Yeo, A. Swamynathan, J. Garlepp, Q. Huynh, Z. W. Tay, P. Chandrasekharan, B. Fellows, I. Rodrigo, S. M. Conolly, Pulsed MPI Relaxometry of Brownian and Néel Field-Dependent Relaxation in Superparamagnetic Magnetite Nanoparticles Confirm Theory and Simulations. Small 2024, 2403283. https://doi.org/10.1002/smll.202403283
Tay ZW, Saayujya C, Le Huynh Q, Bryan JT, Kuo R, Yu E, Fellows B, Chandrasekharan P, Conolly S. Chapter 14 - Magnetic nanoparticles in magnetic particle imaging: principles and applications. In: Wu K, Wang J-P, editors. Magnetic Nanoparticles in Nanomedicine: Woodhead Publishing; 2024. p. 401-57.
Yousuf M, Chandrasekharan P*, Conolly S. Magnetic Particle Imaging for the Evaluation of Gastrointestinal Health by Measuring Gastrointestinal Permeability. International Journal on Magnetic Particle Imaging (IJMPI). 2023;9(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2023.2303062.
Kuo R, Saayujya C, Yeo KH, Rodrigo I, Chandrasekharan P*, Conolly S. High resolution magnetic nanoparticle tracers for CAR-T cell tracking, stroke, GI bleed and pulmonary embolism imaging in Magnetic Particle Imaging. International Journal on Magnetic Particle Imaging (IJMPI). 2023;9(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2023.2303068.
Kuo R, Saayujya C, Yeo KH, Huynh Q, Rodrigo I, Chandrasekharan P, Conolly S. Brownian superparamagnetic nanoparticles for cell viability assessment in Magnetic Particle Imaging. International Journal on Magnetic Particle Imaging (IJMPI). 2023;9(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2023.2303067.
Fung KLB, Colson C, Bryan J, Saayujya C, Mokkarala-Lopez J, Hartley A, Yousuf K, Kuo R, Lu Y, Fellows BD, Chandrasekharan P, Conolly SM. First Superferromagnetic Remanence Characterization and Scan Optimization for Super-Resolution Magnetic Particle Imaging. Nano Letters. 2023;23(5):1717-25. doi: 10.1021/acs.nanolett.2c04404.
Doyle O, Bryan J, Kim M, Saayujya C, Nazarian S, Mokkarala-Lopez J, Kuo R, Yousuf M, Chandrasekharan P, Fellows B, Conolly S. Temperature-Dependent Changes in Resolution and Coercivity of Superparamagnetic and Superferromagnetic Iron Oxide Nanoparticles. International Journal on Magnetic Particle Imaging (IJMPI). 2023;9(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2023.2303056.
Chandrasekharan P*, Kuo R, Fung KLB, Saayujya C, Bryan J, Yousuf M, Fellows B, Colson C, Huynh Q, Doyle O, Hartley A, Yousuf K, Goodwill P, Conolly S. Magnetic Particle Imaging in Vascular Imaging, Immunotherapy, Cell Tracking, and Noninvasive Diagnosis. Molecular Imaging. 2023;2023:4131117. doi: 10.1155/2023/4131117.
Yeo KH, Rodrigo I, Kuo R, Chandrasekharan P, Fellows B, Conolly S. Characterizing the performance of commercial magnetic particles for magnetic particle imaging. International Journal on Magnetic Particle Imaging (IJMPI). 2022;8(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2022.2203080.
Tay ZW, Savliwala S, Hensley D, Chandrasekharan P, Fung B, Colson C, Fellows B, Rivera-Jimenez S, Olivo M, Rinaldi C, Conolly S. Superferromagnetic iron oxide: a new paradigm for color multiplex and FRET-like nanoscale 'ruler' for magnetic particle imaging: SPIE; 2022.
Saayujya C, Fung KB, Huynh Q, Colson C, Fellows B, Chandrasekharan P, Conolly SM. Computational modeling of superferromagnetism in finite-length chains of superparamagnetic Iron Oxide tracers for use in super-resolution Magnetic Particle Imaging. International Journal on Magnetic Particle Imaging (IJMPI). 2022;8(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2022.2203052.
Kuo R, Fung B, Chandrasekharan P*, Huynh Q, Saayujya C, Bryan J, Yeo KH, Rodrigo I, Fellows B, Conolly S. Non-radioactive imaging of bone marrow using antibody-conjugated nanoparticles in magnetic particle imaging. International Journal on Magnetic Particle Imaging (IJMPI). 2022;8(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2022.2203087.
Kuo R, Chandrasekharan P*, Fung KLB, Conolly S. In vivo therapeutic cell tracking using magnetic particle imaging. International Journal on Magnetic Particle Imaging (IJMPI). 2022;8(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2022.2203069.
Fung KLB, Colson C, Bryan J, Fellows BD, Saayujya C, Chandrasekharan P, Rinaldi C, Conolly S. Elucidating super-resolution Magnetic Particle Imaging: superferromagnetic remanence decay through MPI signal evolution informs super-resolution MPI scan strategies. International Journal on Magnetic Particle Imaging (IJMPI). 2022;8(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2022.2203051.
Fung KLB, Chandrasekharan P*#, Zhou XY, Cui W, Fong L, Conolly S. Rapid in situ labelling and tracking of neutrophils and macrophages to inflammation using antibody-functionalized MPI tracers. International Journal on Magnetic Particle Imaging (IJMPI). 2022;8(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2022.2203070.
Colson C, Fung KB, Bryan J, Tay ZW, Fellows BD, Saayuja C, Kuo R, Chandrasekharan P, Conolly SM. Evidence that SPIO Chain Formation is Essential for High-Resolution MPI. bioRxiv. 2022:2022.11.27.518061. doi: 10.1101/2022.11.27.518061.
Bryan J, Fellows B, Chandrasekharan P, Conolly S. Optimizing magnetic particle image resolution using superferromagnetic nanoparticles modified through post-synthesis oxidation. International Journal on Magnetic Particle Imaging (IJMPI). 2022;8(1 Suppl 1). doi: https://doi.org/10.18416/IJMPI.2022.2203050.
Tay ZW, Savliwala S, Hensley DW, Fung KLB, Colson C, Fellows BD, Zhou X, Huynh Q, Lu Y, Zheng B, Chandrasekharan P, Rivera-Jimenez SM, Rinaldi-Ramos CM, Conolly SM. Superferromagnetic Nanoparticles Enable Order-of-Magnitude Resolution & Sensitivity Gain in Magnetic Particle Imaging. Small Methods. 2021;5(11):2100796. doi: https://doi.org/10.1002/smtd.202100796.
Tay ZW, Chandrasekharan P, Fellows BD, Arrizabalaga IR, Yu E, Olivo M, Conolly SM. Magnetic Particle Imaging: An Emerging Modality with Prospects in Diagnosis, Targeting and Therapy of Cancer. Cancers. 2021;13(21):5285. PubMed PMID: doi:10.3390/cancers13215285.
Chandrasekharan P*, Tay ZW, Zhou XY, Yu EY, Fung BKL, Colson C, Fellows BD, Lu Y, Huynh Q, Saayujya C, Keselman P, Hensley D, Lu K, Orendorff R, Konkle J, Saritas EU, Zheng B, Goodwill P, Conolly S. Chapter 15 - Magnetic Particle Imaging for Vascular, Cellular and Molecular Imaging. In: Ross BD, Gambhir SS, editors. Molecular Imaging (Second Edition): Academic Press; 2021. p. 265-82.
Chandrasekharan P*, Fung KLB, Zhou XY, Cui W, Colson C, Mai D, Jeffris K, Huynh Q, Saayujya C, Kabuli L, Fellows B, Lu Y, Yu E, Tay ZW, Zheng B, Fong L, Conolly SM. Non-radioactive and sensitive tracking of neutrophils towards inflammation using antibody functionalized magnetic particle imaging tracers. Nanotheranostics. 2021;5(2):240-55. doi: 10.7150/ntno.50721.
Yang C-T, Hattiholi A, Selvan ST, Yan SX, Fang W-W, Chandrasekharan P, Koteswaraiah P, Herold CJ, Gulyás B, Aw SE, He T, Ng DCE, Padmanabhan P. Gadolinium-based bimodal probes to enhance T1-Weighted magnetic resonance/optical imaging. Acta Biomaterialia. 2020;110:15-36. doi: https://doi.org/10.1016/j.actbio.2020.03.047.
Tay ZW, Hensley DW, Chandrasekharan P, Zheng B, Conolly SM. Optimization of Drive Parameters for Resolution, Sensitivity and Safety in Magnetic Particle Imaging. IEEE Transactions on Medical Imaging. 2020;39(5):1724-34. doi: 10.1109/TMI.2019.2957041.
Lu Y, Rivera-Rodriguez A, Tay ZW, Hensley D, Fung KLB, Colson C, Saayujya C, Huynh Q, Kabuli L, Fellows B, Chandrasekharan P, Rinaldi C, Conolly S. Combining magnetic particle imaging and magnetic fluid hyperthermia for localized and image-guided treatment. International Journal of Hyperthermia. 2020;37(3):141-54. doi: 10.1080/02656736.2020.1853252.
Chandrasekharan P*, Tay ZW, Hensley D, Zhou XY, Fung BKL, Colson C, Lu Y, Fellows BD, Huynh Q, Saayujya C, Yu E, Orendorff R, Zheng B, Goodwill P, Rinaldi C, Conolly S. Using magnetic particle imaging systems to localize and guide magnetic hyperthermia treatment: tracers, hardware, and future medical applications. Theranostics. 2020;10(7):2965-81. doi: 10.7150/thno.40858.
Tay ZW, Hensley D, Ma J, Chandrasekharan P, Zheng B, Goodwill P, Conolly S. Pulsed Excitation in Magnetic Particle Imaging. IEEE Transactions on Medical Imaging. 2019;38(10):2389-99. doi: 10.1109/TMI.2019.2898202.
Hensley D, Tay ZW, Zheng B, Ma J, Booijink NO, Chandrasekharan P, Goodwill P, Conolly S. Pulsed MPI for Improved Resolution and Contrast. IWMPI. 2019.
Zhou XY, Tay ZW, Chandrasekharan P, Yu EY, Hensley DW, Orendorff R, Jeffris KE, Mai D, Zheng B, Goodwill PW, Conolly SM. Magnetic particle imaging for radiation-free, sensitive and high-contrast vascular imaging and cell tracking. Current Opinion in Chemical Biology. 2018;45:131-8. doi: https://doi.org/10.1016/j.cbpa.2018.04.014.
Tay ZW, Chandrasekharan P, Zhou XY, Yu E, Zheng B, Conolly S. In vivo tracking and quantification of inhaled aerosol using magnetic particle imaging towards inhaled therapeutic monitoring. Theranostics. 2018;8(13):3676-87. doi: 10.7150/thno.26608.
Tay ZW, Chandrasekharan P, Chiu-Lam A, Hensley DW, Dhavalikar R, Zhou XY, Yu EY, Goodwill PW, Zheng B, Rinaldi C, Conolly SM. Magnetic Particle Imaging-Guided Heating in Vivo Using Gradient Fields for Arbitrary Localization of Magnetic Hyperthermia Therapy. ACS Nano. 2018;12(4):3699-713. doi: 10.1021/acsnano.8b00893.
Lv YB, Chandrasekharan P#, Li Y, Liu XL, P. Avila J, Yang Y, Chuang KH, Liang X-J, Ding J. Magnetic resonance imaging quantification and biodistribution of magnetic nanoparticles using T1-enhanced contrast. Journal of Materials Chemistry B. 2018;6(10):1470-8. doi: 10.1039/C7TB03129G.
Chandrasekharan P*, Yang C-T. Nanobiomaterials for Molecular Imaging. Nanobiomaterials2018. p. 259-79.
Chandrasekharan P*, Tay ZW, Zhou XY, Yu E, Orendorff R, Hensley D, Huynh Q, Fung KLB, VanHook CC, Goodwill P, Zheng B, Conolly S. A perspective on a rapid and radiation-free tracer imaging modality, magnetic particle imaging, with promise for clinical translation. The British Journal of Radiology. 2018;91(1091):20180326. doi: 10.1259/bjr.20180326. PubMed PMID: 29888968.
Balasundaram G, Ding L, Li X, Attia ABE, Dean-Ben XL, Ho CJH, Chandrasekharan P, Tay HC, Lim HQ, Ong CB, Mason RP, Razansky D, Olivo M. Noninvasive Anatomical and Functional Imaging of Orthotopic Glioblastoma Development and Therapy using Multispectral Optoacoustic Tomography. Translational Oncology. 2018;11(5):1251-8. doi: https://doi.org/10.1016/j.tranon.2018.07.001
Zheng B, Yu E, Orendorff R, Lu K, Konkle JJ, Tay ZW, Hensley D, Zhou XY, Chandrasekharan P, Saritas EU, Goodwill PW, Hazle JD, Conolly SM. Seeing SPIOs Directly In Vivo with Magnetic Particle Imaging. Molecular Imaging and Biology. 2017;19(3):385-90. doi: 10.1007/s11307-017-1081-y.
Yu EY, Chandrasekharan P#, Berzon R, Tay ZW, Zhou XY, Khandhar AP, Ferguson RM, Kemp SJ, Zheng B, Goodwill PW, Wendland MF, Krishnan KM, Behr S, Carter J, Conolly SM. Magnetic Particle Imaging for Highly Sensitive, Quantitative, and Safe in Vivo Gut Bleed Detection in a Murine Model. ACS Nano. 2017;11(12):12067-76. doi: 10.1021/acsnano.7b04844.
Keselman P, Yu EY, Zhou XY, Goodwill PW, Chandrasekharan P, Ferguson RM, Khandhar AP, Kemp SJ, Krishnan KM, Zheng B, Conolly SM. Tracking short-term biodistribution and long-term clearance of SPIO tracers in magnetic particle imaging. Physics in Medicine & Biology. 2017;62(9):3440. doi: 10.1088/1361-6560/aa5f48.
Liu XL, Ng CT, Chandrasekharan P#, Yang HT, Zhao LY, Peng E, Lv YB, Xiao W, Fang J, Yi JB, Zhang H, Chuang K-H, Bay BH, Ding J, Fan HM. Synthesis of Ferromagnetic Fe0.6Mn0.4O Nanoflowers as a New Class of Magnetic Theranostic Platform for In Vivo T1-T2 Dual-Mode Magnetic Resonance Imaging and Magnetic Hyperthermia Therapy. Advanced Healthcare Materials. 2016;5(16):2092-104. doi: https://doi.org/10.1002/adhm.201600357.
Jackson AW, Chandrasekharan P#*, Ramasamy B, Goggi J, Chuang K-H, He T, Robins EG. Octreotide Functionalized Nano-Contrast Agent for Targeted Magnetic Resonance Imaging. Biomacromolecules. 2016;17(12):3902-10. doi: 10.1021/acs.biomac.6b01256.
Attia ABE, Ho CJH, Chandrasekharan P#, Balasundaram G, Tay HC, Burton NC, Chuang K-H, Ntziachristos V, Olivo M. Multispectral optoacoustic and MRI coregistration for molecular imaging of orthotopic model of human glioblastoma. Journal of Biophotonics. 2016;9(7):701-8. doi: https://doi.org/10.1002/jbio.201500321.
Yang C-T, Tao H, Jackson AW, Chandrasekharan P, Padmanabhan P, Gulyás B, Halldin C. Biocompatible branched copolymer nanoparticles prepared by RAFT polymerization as MRI/PET bimodal tracers. EJNMMI Physics. 2015;2(1):A90. doi: 10.1186/2197-7364-2-S1-A90.
Li Y, Zhou Q-L, Sun W, Chandrasekharan P, Cheng HS, Ying Z, Lakshmanan M, Raju A, Tenen DG, Cheng S-Y, Chuang K-H, Li J, Prabhakar S, Li M, Tergaonkar V. Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation. Nature Cell Biology. 2015;17(10):1327-38. doi: 10.1038/ncb3240.
Jackson AW, Chandrasekharan P#, Shi J, Rannard SP, Liu Q, Yang C-T, He T. Synthesis and in vivo magnetic resonance imaging evaluation of biocompatible branched copolymer nanocontrast agents. International Journal of Nanomedicine. 2015;10:5895-907. doi: 10.2147/IJN.S88764.
Chandrasekharan P, Yang C-T, Nasrallah FA, Tay HC, Chuang K-H, Robins EG. Pharmacokinetics of Gd(DO3A-Lys) and MR imaging studies in an orthotopic U87MG glioma tumor model. Contrast Media & Molecular Imaging. 2015;10(3):237-44. doi: https://doi.org/10.1002/cmmi.1634.
Attia ABE, Ho CJH, Chandrasekharan P#, Balasundaram G, Chuang K-H, Olivo M, editors. Molecular Photoacoustic Imaging of Orthotopic Glioblastoma. Optics in the Life Sciences; 2015 2015/04/12; Vancouver: Optica Publishing Group.
Yang C-T, Chandrasekharan P, He T, Poh Z, Raju A, Chuang K-H, Robins EG. An intravascular MRI contrast agent based on Gd(DO3A-Lys) for tumor angiography. Biomaterials. 2014;35(1):327-36. doi: https://doi.org/10.1016/j.biomaterials.2013.10.006.
Steinberg JD, Raju A, Chandrasekharan P, Yang C-T, Khoo K, Abastado J-P, Robins EG, Townsend DW. Negative contrast Cerenkov luminescence imaging of blood vessels in a tumor mouse model using [68Ga]gallium chloride. EJNMMI Research. 2014;4(1):15. doi: 10.1186/2191-219X-4-15.
Fang J, Chandrasekharan P#, Liu X-L, Yang Y, Lv Y-B, Yang C-T, Ding J. Manipulating the surface coating of ultra-small Gd2O3 nanoparticles for improved T1-weighted MR imaging. Biomaterials. 2014;35(5):1636-42. doi: https://doi.org/10.1016/j.biomaterials.2013.11.032.
Liu J, Li K, Geng J, Zhou L, Chandrasekharan P, Yang C-T, Liu B. Single molecular hyperbranched nanoprobes for fluorescence and magnetic resonance dual modal imaging. Polymer Chemistry. 2013;4(5):1517-24. doi: 10.1039/C2PY20837G.
Li K, Ding D, Prashant C, Qin W, Yang C-T, Tang BZ, Liu B. Gadolinium-Functionalized Aggregation-Induced Emission Dots as Dual-Modality Probes for Cancer Metastasis Study. Advanced Healthcare Materials. 2013;2(12):1600-5. doi: https://doi.org/10.1002/adhm.201300135.
Choo ESG, Peng E, Rajendran R, Chandrasekharan P, Yang C-T, Ding J, Chuang K-H, Xue J. Superparamagnetic Nanostructures for Off-Resonance Magnetic Resonance Spectroscopic Imaging. Advanced Functional Materials. 2013;23(4):496-505. doi: https://doi.org/10.1002/adfm.201200275.
Peng E, Choo ESG, Chandrasekharan P, Yang C-T, Ding J, Chuang K-H, Xue JM. Synthesis of Manganese Ferrite/Graphene Oxide Nanocomposites for Biomedical Applications. Small. 2012;8(23):3620-30. doi: https://doi.org/10.1002/smll.201201427.
Chandrasekharan P, Yong C-X, Poh Z, He T, He Z, Liu S, Robins EG, Chuang K-H, Yang C-T. Gadolinium chelate with DO3A conjugated 2-(diphenylphosphoryl)-ethyldiphenylphosphonium cation as potential tumor-selective MRI contrast agent. Biomaterials. 2012;33(36):9225-31. doi: https://doi.org/10.1016/j.biomaterials.2012.08.071.
Tan YF, Chandrasekharan P, Maity D, Yong CX, Chuang K-H, Zhao Y, Wang S, Ding J, Feng S-S. Multimodal tumor imaging by iron oxides and quantum dots formulated in poly (lactic acid)-d-alpha-tocopheryl polyethylene glycol 1000 succinate nanoparticles. Biomaterials. 2011;32(11):2969-78. doi: https://doi.org/10.1016/j.biomaterials.2010.12.055.
Maity D, Pradhan P, Chandrasekharan P, Kale SN, Shuter B, Bahadur D, Feng S-S, Xue J-M, Ding J. Synthesis of Hydrophilic Superparamagnetic Magnetite Nanoparticles via Thermal Decomposition of Fe(acac)3 in 80 Vol% TREG + 20 Vol% TREM. Journal of Nanoscience and Nanotechnology. 2011;11(3):2730-4. doi: 10.1166/jnn.2011.2693.
Maity D, Chandrasekharan P, Pradhan P, Chuang K-H, Xue J-M, Feng S-S, Ding J. Novel synthesis of superparamagnetic magnetite nanoclusters for biomedical applications. Journal of Materials Chemistry. 2011;21(38):14717-24. doi: 10.1039/C1JM11982F.
Chandrasekharan P, Maity D, Yong CX, Chuang K-H, Ding J, Feng S-S. Vitamin E (d-alpha-tocopheryl-co-poly(ethylene glycol) 1000 succinate) micelles-superparamagnetic iron oxide nanoparticles for enhanced thermotherapy and MRI. Biomaterials. 2011;32(24):5663-72. doi: https://doi.org/10.1016/j.biomaterials.2011.04.037.
Prashant C, Dipak M, Yang C-T, Chuang K-H, Jun D, Feng S-S. Superparamagnetic iron oxide – Loaded poly (lactic acid)-d-α-tocopherol polyethylene glycol 1000 succinate copolymer nanoparticles as MRI contrast agent. Biomaterials. 2010;31(21):5588-97. doi: https://doi.org/10.1016/j.biomaterials.2010.03.070.
Prashant C, Dipak M, Chang-Tong Y, Kai-Hsiang C, Jun D, Si-Shen F. Formulation of iron oxides by nanoparticles of poly-lactide- co-D-α-tocopherol-polyethylene glycol 1000 succinate biodegradable polymer for magnetic resonance imaging. Journal of Applied Physics. 2010;107(9). doi: 10.1063/1.3357341.
Maity D, Chandrasekharan P, Yang C-T, Chuang K-H, Shuter B, Xue J-M, Ding J, Feng S-S. Facile synthesis of water-stable magnetite nanoparticles for clinical MRI and magnetic hyperthermia applications. Nanomedicine. 2010;5(10):1571-84. doi: 10.2217/nnm.10.77. PubMed PMID: 21143034.
Maity D, Chandrasekharan P, Si-Shen F, Xue J-M, Ding J. Polyol-based synthesis of hydrophilic magnetite nanoparticles. Journal of Applied Physics. 2010;107(9). doi: 10.1063/1.3355898.
Maity D, Chandrasekharan P, Feng SS, Jun D, editors. Synthesis and studies of APTES functionalized magnetite nanoparticles. 2010 International Conference on Nanoscience and Nanotechnology; 2010 22-26 Feb. 2010.
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Abstract Reviewer for the World molecular Imaging Congress (WMIC) (2017 - present)
Abstract Reviewer International Workshop on Magnetic Particle Imaging (IWMPI)(2019-2022)
Abstract Reviewer Drug Delivery Conference, Malaysia (2012)
Abstract Reviewer IEEE conference - 1st Biomedical Conference of the Middle-East (MECBME), Sharjah, UAE (2011)